Rare Diseases

Lorne Clarke, BSc, MDCM, FRCPC, FCCMG

Dr. Lorne Clarke is a professor of medical genetics at the University of British Columbia, Canada and is a clinical and biochemical geneticist in the Provincial Medical Genetics Program for the Province of British Columbia. He served as medical director of the provincial program for 5 years and is currently the acting head of the genetics research cluster at the Child and Family Health Research Institute at UBC. He received his initial training in biochemistry and medicine at McGill University and is certified in paediatrics, clinical genetics and biochemical genetics. He has been active in fundamental research for over 20 years studying the basic pathophysiology of lysosomal storage disease with particular interest in biomarkers of disease and murine models. His group was the first to develop a mouse model of MPS I and recently has produced mouse models of Gaucher disease. In addition to basic science, Dr. Clarke’s group is also actively participates in clinical trials involving lysosomal storage diseases as well as other rare genetic disorders.